Forwarded by Freeman & Co's Express Marysville. Clearly struck greenish blue handstamp (Thomas FRE-104a) on 1851 folded letter to San Francisco, appears to say
"Refused" in pencil at top left, edge wear and file fold, Very Fine strike of this scarce early Freeman & Co. handstamp from the 1850 iteration of the express, illustrated in Thomas on p. 321
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E. 400-500